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Phen375 Vs PhenRx – The Popular Nexgen Pill Review

Complying to many requests sent to us asking for a review on phenrx and how it is compared to Phen375.

The misconception we perceived from our followers need to be addressed and emphasized again.

Both products or any other fat burners are not magic pills and you are not going to lose 10 lbs. a week by only consuming a pill a day.

There is no such product available and properly won’t be in the next 20 to 30 years.

Phenrx and Phen375 mainly target metabolic function, fat burning, and enhanced lean body mass.

However, letting fat burners doing the work alone won’t do any good on the long term as we are here to change your lifestyle and attitude positively.

Bonus: Do you want to build 7 lbs of muscle… While losing 3 lbs of fat, in less than 30 days? DOWNLOAD FREE E-Book NOW

The fastest way to reach this is through fat burner supplements

Comparison between Phen375 vs PhenRx






Clinical Studies


  • Increase metabolic rate based on its thermogenisis effect leading to more energy.
  • Weight loss rate from 3-5 lbs per week.
  • Anti-depressant effect to avoid any depression during weight loss journey.
  • Appetite suppression; avoid food craving


  • appetite suppression
  • energy enhancement and increased mental focus


Side effects


2014None; rare mild headachesWorst-fatburner-reviewsCause heart palpitations and a whole range of side effects (upset stomach and sleeplessness). It’s ingredients (Synephrine) has been linked to causing heart attacks and strokes.
Best Uses


2014Bodybuilding, Energy Boost, Maintaining weight, Weight loss2014Energy Boost, Maintaining weight, Weight loss
Money-back Guarantee


201430 daysWorst-fatburner-reviewsNo
Appetite suppressant2014Yes2014Yes
Weight loss effect20143-5 lbs per weekWorst-fatburner-reviews1-2 lbs per week
Reorder rate2014HighWorst-fatburner-reviewsLow


2014It can be purchased online from the official website2014It can be purchased online from it’s official website or GNC
User Reviews

testimonials-on-phentermine 37.5

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Official Website

Nexagon official website

PhenRx User Reviews

According to Nexgen Biolabs they designed Phenrx PM to be a night time friendly fat loss supplement their claim is it is very similar to Phentermine effect although it wouldn’t cause the overstimulated and insomnia side effects.

PhenRx Mechanism of Action / How does it work

This is directly quoted from the official site

PhenRx is clinically proven to block off & deactivate the Alpha-2 receptor and antagonize alpha 2-adrenoceptors, allowing lipolysis or fat burning to occur while also stimulating lipolysis to continue from beta adrenoceptor agonism, giving you a the ultimate dual receptor fat burning stimulus!

It doesn’t need a Phd nutrition specialist to know this is just pure nonsense. Manipulating scientific words to give the impression that it’s something great however it is not. Marketing is one thing but deception is another. And that is obviously not marketing.

 PhenRx Ingredients

There is in fact much less transparency when it comes to disclosing the ingredients of the supplement regarding the concentration for each component. As an end user you might not understand 80% of the ingredients but it’s essential for many nutrition specialists to research each and every ingredient and see the safety concentration for each one. The ingredients are Trimethylxanthine, Beta-Phenylethylamine, Synephrine HCL, N-dimethyl-4-hydroxyphenylethylamine, Schizandrol AGreen Tea Extract, Magnolia Bark Extract, Phosphatidylserine, Coleus Forskohlii, Raspberry Ketones, L-Theanine, 7-Keto DHEA, Gamma-aminobutyric Acid, Melatonin, Black Pepper Extract.

Briefed insights on main active ingredients;

Trimethylxanthine is just caffeine. It can be effective as part of a weight loss diet because it raises the speed of the metabolism.

Beta-Phenylethylamine is a mood stimulant that slows down dopamine receptors. It also speeds up dopamine production. It causes a short-lived high effect but is quickly metabolized.

Synephrine HCL is a synthetic appetite supplement

Pill_Side_effectsSide effects of PhenRx

Every individual will react differently, but early reports and reviews of phenrx shows;

  • Vivid dreams
  • Headaches
  • Shakiness
  • Swollen limbs
  • Upset stomach
  • Nausea
  • Racing heart

These kind of sideeffects are not mentioned on the official website of the product. These were reported by genuine customers from Amazon , ebay and private blogs.


PhenRx User Reviews on Amazon

this is an overall customer review

Amazon users on PhenRx

Click to enlarge each picture and read its content

PhenRx Testimonial

PhenRx Testimonial3

PhenRx Testimonial2

PhenRx Testimonial1

Bottom line on PhenRx

The aim goal of PhenRx is burn fat and increase metabolic rate without side effects.

However our research shows that it can help you lose weight but the impact factor of its side effects is huge and intolerable because of “Synephrine HCL”.

Its recommended alternative is Phen375. Although this product has superior advantages over PhenRx based on recent clinical studies and users feedbacks.

The downside might be in it’s price which many would be sensitive to. Checkout more details from the users on Phen375.

About the author

Saleh is a writer, healthcare professional, and periodically provides with articles, recent case studies and product reviews.He dedicated his life to transforming the lives of the skinny, out of shape, scrawny wimpy guys & skinny girls - helping them become healthier, fitter and more confident in their bodies. You can also read more About me.

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